Rafael Nadal has advanced to the third round of the Barcelona Open, beating Leonard Mayer 6-7, 6-4, 6-2.
The top seed will next face fellow Spaniard David Ferrer, who defeated 15th-seeded Lucas Pouille 6-3, 6-1.
Meanwhile, Monte Carlo Masters champion Fabio Fognini has withdrawn from the tournament because of a hamstring injury.
Elsewhere, seventh-seeded Daniil Medvedev overcame Albert Ramos-Vinolas 6-3, 2-6, 6-1, while American Mackenzie McDonald advanced with a 6-3, 6-2 win over 11th-seeded Gilles Simon.
There were also wins for Grigor Dimitrov, Benoit Paire, Felix Auger-Aliassime and Roberto Carballes Baena.