A missile hit a medical facility in the city of Taba on the Red Sea near the Israeli border early on Friday, wounding six people, the Egyptian Cairo News Channel reported.
The channel said, citing sources, that the explosion was related to the ongoing fighting between Israel and Hamas in Gaza.
A witness in Taba, which is about 220 km from Gaza, said he heard an explosion and saw thick smoke and dust rising.
The channel reported the missile hit the ambulance building in Taba and the residence designated for the administration of the city hospital.
The Israeli army stated that it was aware of this security incident, adding that it "occurred outside our borders".
Taba, in Egypt's Sinai Peninsula, is popular with tourists. It is about a three-hour drive from Egypt's Red Sea resort town of Sharm el-Sheikh.
Qatar's prime minister said on Sunday that efforts to reach a new ceasefire in Gaza have made some progress but an agreement between Israel and Hamas to end the war remains elusive.
A huge blast most likely caused by the explosion of chemical materials killed at least 18 people and injured more than 700 on Saturday at Iran's biggest port, Bandar Abbas, Iranian state media reported.
The UN Refugee Agency (UNHCR) and the UN Office for the Coordination of Humanitarian Affairs (OCHA) have sounded the alarm over severe funding shortfalls that are hindering life-saving humanitarian aid in countries including Nigeria, Burundi, and Colombia.
A number of people were killed and multiple others were injured in Vancouver after a vehicle drove into a crowd at a Filipino street festival in the western Canadian city, police said on Saturday.